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Contract Services

 

Mechanism of Action

 

The following assays are offered by HemoGenix® to study mechanism of action. These are available as individual assays or can be multiplexed with other HemoGenix® proprietary platforms. 

 

  • FloDiff™: Membrane expression marker detection, cell cycle, ploidy, apoptosis (depends on the species and cell markers available).
  • Membrane integrity: LDH and/or PI assays.
  • Micronucleus assay.
  • Soft agar assay.
  • Chemotaxis/ migration assays.
  • GFkine™: Growth factor/cytokine production/release.
  • Phospodiesterase assays.
  • Kinase assays.
  • Protease assay.
  • P-Glycoprotein assay.
  • Monoamine oxidate assay.
  • UDPglucuronosytransferase (UGT) assay.
  • Mitochondrial ToxGlo™: Mitochondrial dysfunction assay.
  • Glutathione Assay: Oxidative stress.
  • Nitric oxide (NO) assay
  • Lipid peroxidation assay
  • Reactive oxygen species assays
  • OxyFLOW™: A flow cytometric oxidative DNA damage assay.
  • Biochemical apoptosis assays: CaspaseGlo™.
  • Cytochrome P450 assays.
  • Cellular drug-drug interaction studies.

 

For more information, please contact HemoGenix directly at (719) 264-620 or info@hemogenix.com