Mesenchymal Stem Cells
Assays for the Mesenchymal System
Mesenchymal stem cells (MSC) or mesenchymal progenitor cells (MPC) are present in several tissues, including bone marrow, cord blood and adipose tissue, and can also be produced from induce pluripotential stem cells (iPSC). They are cells that are usually characterized by their phenotypic profile, being positive for CD73, CD90 and CD105, to mention just a few. Mesenchymal stem/progenitor cells represent a proliferating population, whose proliferation ability and potential can be quantified using:
- MSCGlo™-96 Research with a bioluminescence endpoint.
- MSCGlo™-Real Time, to measure the growth kinetics of MSC/MPS with a bioluminescence endpoint.
- MSCFluor™-96 Research, with a fluorescence endpoint.
- MSCLight™-96 Research, with an absorbance/coloimetric endpoint.
These assays can be implemented for many regenerative medicine applications, but more specific, clinically -relevent assays are also available from HemoGenix.
- MSCGlo™-96 HuQC, to determine MSC/MPC quality before and after different processes or procedures.
- MSCGlo™-Potency. The only FDA-compliant potency assay commercially available.
High-throughput mesenchymal toxicity testing can also be performed using:
Human Platelet Lysate and Defined Growth and Differentiation Media
All assays are available with a diversified range of high perform media or human platelet lysate to replace fetal bovine serum (FBS). These reagents are also available individually.